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BPC-157 (5mg)

BPC-157 (5mg)

$35.00 USD
$35.00 USD
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Overview:

BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) derived from a partial sequence of human gastric juice protein BPC. It is renowned for its broad-spectrum healing properties, including effects on muscles, tendons, ligaments, nerves, gastrointestinal tissues, and vascular structures.

Originally studied for its role in gastrointestinal ulcer protection, BPC-157 has demonstrated potent angiogenic, anti-inflammatory, and fibroblast-activating effects in a wide array of preclinical models. It is unique among peptides for its high oral stability, systemic bioactivity, and ability to modulate multiple cellular signaling pathways related to tissue integrity and repair.

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PubChem Information

https://pubchem.ncbi.nlm.nih.gov/compound/9941957

What is BPC-157?

  • Mechanism of Action:

    BPC-157 exerts its effects primarily through angiogenic regulation, nitric oxide modulation, and growth factor pathway activation:

    • Activates vascular endothelial growth factor receptor 2 (VEGFR2), promoting angiogenesis and re-endothelialization of damaged vessels
    • Interacts with the nitric oxide (NO) system, enhancing vasodilation, anti-oxidative stress responses, and anti-inflammatory signaling
    • Upregulates fibroblast activity, increasing collagen synthesis, ECM remodeling, and granulation tissue formation
    • Modulates dopaminergic and serotonergic systems, contributing to neuroprotection and behavioral normalization in CNS injury models
    • Enhances expression of growth factors such as EGF, FGF, and TGF-β, leading to improved wound healing, epithelial barrier integrity, and nerve regeneration

    These multimodal effects contribute to its efficacy across diverse injury types—both local and systemic—with minimal toxicity.

  • Preclinical Studies:

    • In rodent studies, BPC-157 accelerates tendon and ligament repair, particularly in the Achilles tendon, medial collateral ligament (MCL), and quadriceps
    • Demonstrates rapid gastrointestinal healing, including resolution of NSAID-induced ulcers, IBD, and anastomotic leakage
    • Reverses muscle crushing injuries and neuropraxia by promoting angiogenesis and axonal outgrowth
    • In models of neurodegeneration and traumatic brain injury, BPC-157 preserves neuronal architecture and modulates neurotransmitter systems
    • Exhibits anti-thrombotic and pro-vascular effects, such as normalization of thrombocyte function and blood flow recovery after ischemia

  • Intended Use:

    • The information provided on this site is intended exclusively for educational and research purposes and should not be interpreted as medical guidance.
    • Research compounds, including BPC-157 are designed solely for laboratory investigation by qualified professionals and are not intended for human use or consumption.
    • The statements presented here have not been evaluated by the U.S. Food and Drug Administration, and the products discussed are not intended to diagnose, treat, cure, or prevent any disease.