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HMG (75 i.u.)

HMG (75 i.u.)

Regular price $59.00 USD
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Overview:

Human Menopausal Gonadotropin (HMG) is a natural gonadotropin preparation derived from the urine of postmenopausal women, containing both follicle-stimulating hormone (FSH) and luteinizing hormone (LH) in biologically active forms. The 75 IU dosage typically refers to 75 International Units of FSH and 75 IU of LH, making it a balanced gonadotropic therapy widely used in fertility treatments and reproductive hormone research.

HMG plays a critical role in stimulating ovarian follicular development in women and spermatogenesis in men, and is commonly administered as part of assisted reproductive protocols such as in vitro fertilization (IVF), intrauterine insemination (IUI), or hypogonadotropic hypogonadism treatment.

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  • Mechanism of Action:

    HMG mimics the natural activity of the pituitary gonadotropins:

    • FSH Activity: Stimulates maturation of ovarian follicles in females and supports Sertoli cell activity for sperm production in males.
    • LH Activity: Triggers ovulation in females and stimulates Leydig cells in the testes to promote testosterone synthesis in males.
    • Together, FSH and LH promote a synchronized reproductive hormonal response.
  • Preclinical and Clinical Studies:

    • Female Fertility: HMG is a mainstay in controlled ovarian hyperstimulation (COH), improving follicular development and pregnancy rates.
    • Male Hypogonadism: Used to treat hypogonadotropic hypogonadism by restoring endogenous testosterone and spermatogenesis.
    • PCOS Management: When combined with hCG or GnRH analogs, HMG can help initiate ovulation in women with polycystic ovary syndrome (PCOS).
    • Animal Models: Extensively used to study reproductive hormone cycles, follicular dynamics, and fertility control in mammals.
  • Intended Use:

    • The information provided on this site is
      intended exclusively for educational and research purposes and should not be interpreted as medical guidance.
    • Research compounds, including HMG, are designed solely for laboratory investigation by qualified professionals and are not intended for human use or consumption.
    • The statements presented here have not been evaluated by the U.S. Food and Drug Administration, and the products discussed are not intended to diagnose, treat, cure, or prevent any disease.