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PEG-MGF (2mg)

PEG-MGF (2mg)

$45.00 USD
$45.00 USD
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PEG-MGF is a chemically modified version of Mechano Growth Factor (MGF), a splice variant of Insulin Like Growth Factor-1 (IGF-1) that is rapidly expressed in skeletal muscle following mechanical overload or injury. PEG-MGF is created by attaching a polyethylene glycol (PEG) moiety to native MGF, which significantly extends its half-life, enhances systemic stability, and improves therapeutic potential.

Due to its unique properties, PEG-MGF is studied for its potential to stimulate muscle regeneration, enhance recovery, and support neuroprotection in degenerative conditions.

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What is PEG MGF?

  • Mechanism of Action:

    PEG-MGF mimics the biological effects of native MGF while improving its pharmacokinetic profile:

    • Satellite Cell Activation: Promotes the activation and proliferation of muscle satellite cells, leading to muscle repair and growth.
    • Tissue Regeneration: Enhances repair of damaged myofibers and supports muscle hypertrophy following injury or exercise.
    • Neuroprotection: Exhibits potential in protecting neuronal tissue and enhancing axon regeneration in certain CNS conditions.
    • Delayed Apoptosis: Helps preserve cellular integrity in stressful or catabolic states.

    The PEGylation process helps the peptide resist rapid degradation, providing a prolonged anabolic signal to tissues.

  • Preclinical and Clinical Studies:

    • Muscle Wasting Conditions: Demonstrated benefits in preclinical models of cachexia, sarcopenia, and muscular dystrophy.
    • Post-Exercise Recovery: Enhances muscle regeneration and accelerates recovery following intense training or injury.
    • Nerve Regeneration: Preclinical studies suggest PEG-MGF promotes motor neuron survival and may aid in neurorepair.
    • Bone Healing: When combined with bone scaffolds or stem cells, PEG-MGF shows promise in osteogenesis and fracture recovery.

  • Intended Use:

    • The information provided on this site is intended exclusively for educational and research purposes and should not be interpreted as medical guidance.
    • Research compounds, including PEG- MGF, are designed solely for laboratory investigation by qualified professionals and are not intended for human use or consumption.
    • The statements presented here have not been evaluated by the U.S. Food and Drug Administration, and the products discussed are not intended to diagnose, treat, cure, or prevent any disease.