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Semax (5mg)

Semax (5mg)

$25.00 USD
$25.00 USD
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Overview:

Semax is a synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) developed in Russia and classified as a nootropic and neuroprotective agent. It is a fragment of adrenocorticotropic hormone (ACTH 4–10) that lacks hormonal activity but retains and enhances neuroregulatory functions. Semax is used clinically in Russia and Ukraine for conditions such as stroke recovery, cognitive impairment, and optic nerve disease.

Semax is notable for its central nervous system activity, safety, and broad neurotropic effects, including memory enhancement, mood regulation, and neuroprotection under ischemic conditions.

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PubChem Information

https://pubchem.ncbi.nlm.nih.gov/compound/9811102

What is Semax?

  • Mechanism of Action:

    Semax works through a multifaceted neurochemical profile:

    • Neurotrophic Stimulation: Increases expression of brain-derived neurotrophic factor (BDNF) and NGF in key brain regions, aiding synaptic plasticity and neurogenesis.
    • Dopaminergic & Serotonergic Modulation: Enhances dopamine and serotonin turnover, improving mood, attention, and motivation.
    • Anti-Inflammatory Activity: Modulates cytokine response and oxidative stress, especially post-ischemia.
    • Protection from Ischemic Injury: Inhibits apoptosis and reduces damage in cerebral hypoxia and stroke models.

    The peptide crosses the blood-brain barrier when administered intranasally, allowing for direct CNS acti

  • Preclinical and Clinical Studies:

    Ischemic Stroke Recovery:

    • Promotes neurological recovery and improves motor coordination.
    • Reduces lesion volume and cognitive deficits post-stroke.

    Cognitive Enhancement:

    • mproves working memory, learning, and executive function in animal and limited human studies.
    • Used off-label for ADHD, brain fog, and mental fatigue.

    Anxiety and Stress Modulation:

    • Exhibits anxiolytic effects and enhances adaptive behavior under chronic stress conditions.
    • May help normalize HPA axis activity without stimulating cortisol production.

    Retinal and Optic Nerve Conditions:

    • Protects against optic nerve atrophy and retinal degeneration through trophic support and microvascular enhancement.

  • Intended Use:

    • The information provided on this site is intended exclusively for educational and research purposes and should not be interpreted as medical guidance.
    • Research compounds, including Semax, are designed solely for laboratory investigation by qualified professionals and are not intended for human use or consumption.
    • The statements presented here have not been evaluated by the U.S. Food and Drug Administration, and the products discussed are not intended to diagnose, treat, cure, or prevent any disease.